Adrenal suppression and Cushing's syndrome secondary to ritonavir and budesonide.

نویسندگان

  • D Gray
  • P Roux
  • M Carrihill
  • M Klein
چکیده

To the Editor: Ritonavir is a protease inhibitor used in combination therapy for advanced HIV infection. In South Africa lopinavir/ritonavir is first-line therapy for children under 3 years of age where there is a history of perinatal exposure to the non-nucleoside reverse transcriptase inhibitor (NNRTI) nevirapine.1 Ritonavir is a potent inhibitor of hepatic cytochrome P450-CYP3A4 iso-enzyme activity.

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عنوان ژورنال:
  • South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde

دوره 100 5  شماره 

صفحات  -

تاریخ انتشار 2010